MORF4L2 Protein (Transcript Variant 1) (His tag)
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- Antigène Voir toutes MORF4L2 Protéines
- MORF4L2 (Mortality Factor 4 Like 2 (MORF4L2))
- Type de proteíne
- Recombinant
- Attributs du protein
- Transcript Variant 1
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette MORF4L2 protéine est marqué à la His tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Attributs du produit
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- Recombinant human MORF4L2 (transcript variant 1) protein expressed in E. coli.
- Produced with end-sequenced ORF clone
- Pureté
- > 95 % as determined by SDS-PAGE and Coomassie blue staining
- niveau d'endotoxine
- < 0.1 EU per μg protein as determined by LAL test
- Top Product
- Discover our top product MORF4L2 Protéine
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- Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Commentaires
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The tag is located at the N-terminal.
- Restrictions
- For Research Use only
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- Buffer
- Lyophilized from a 0.2 μM filtered solution of 20 mM Phosphate buffer, 150 mM NaCl, pH 7.4. Stable for at least 6 months from date of receipt under proper storage and handling conditions.
- Stock
- -80 °C
- Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Antigène
- MORF4L2 (Mortality Factor 4 Like 2 (MORF4L2))
- Autre désignation
- Morf4l2 (MORF4L2 Produits)
- Synonymes
- morf4l2 Protein, MORF4L2 Protein, DKFZp468A0820 Protein, MORFL2 Protein, MRGX Protein, 2410017O14Rik Protein, Mrgx Protein, Sid393p Protein, mKIAA0026 Protein, LRRG00119 Protein, mortality factor 4 like 1 Protein, mortality factor 4 like 2 Protein, morf4l1 Protein, MORF4L2 Protein, Morf4l2 Protein
- Sujet
- Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the MSIN3A complex which acts to repress transcription by deacetylation of nucleosomal histones. [UniProtKB/Swiss-Prot Function]
- Poids moléculaire
- 33.4 kDa
- NCBI Accession
- NP_001135890
- Pathways
- Regulation of Muscle Cell Differentiation
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