NEDD4 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Antigène Voir toutes NEDD4 Protéines
- NEDD4 (Neural Precursor Cell Expressed, Developmentally Down-Regulated 4, E3 Ubiquitin Protein Ligase (NEDD4))
- Type de proteíne
- Recombinant
- Attributs du protein
- Transcript Variant 1
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette NEDD4 protéine est marqué à la Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Attributs du produit
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- Recombinant human NEDD4 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Pureté
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product NEDD4 Protéine
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- Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Commentaires
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Stock
- -80 °C
- Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Antigène
- NEDD4 (Neural Precursor Cell Expressed, Developmentally Down-Regulated 4, E3 Ubiquitin Protein Ligase (NEDD4))
- Autre désignation
- Nedd4 (NEDD4 Produits)
- Synonymes
- NEDD4-1 Protein, RPF1 Protein, AA959633 Protein, AL023035 Protein, AU019897 Protein, E430025J12Rik Protein, Nedd4-1 Protein, Nedd4a Protein, mKIAA0093 Protein, CG32184 Protein, CG42279 Protein, CG7555 Protein, DNedd4 Protein, Dmel\\CG42279 Protein, Dmel_CG32184 Protein, Dmel_CG7555 Protein, dNedd4 Protein, dNedd4-1 Protein, nedd4 Protein, GB16853 Protein, NEDD4 Protein, Nedd4 Protein, neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase Protein, neural precursor cell expressed, developmentally down-regulated 4 Protein, CG42279 gene product from transcript CG42279-RJ Protein, E3 ubiquitin-protein ligase Nedd-4 Protein, E3 ubiquitin-protein ligase NEDD4 Protein, NEDD4 Protein, Nedd4 Protein, LOC411723 Protein, LOC100457150 Protein, nedd4 Protein, LOC100547485 Protein
- Sujet
- This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation. The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and, a C-terminal HECT ubiquitin ligase catalytic domain. It plays critical role in the regulation of a number of membrane receptors, endocytic machinery components and the tumor suppressor PTEN.
- Poids moléculaire
- 104 kDa
- NCBI Accession
- NP_006145
- Pathways
- Signalisation Notch, Intracellular Steroid Hormone Receptor Signaling Pathway, Skeletal Muscle Fiber Development, Signaling Events mediated by VEGFR1 and VEGFR2
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