Neuroligin 3 Protein (NLGN3) (Myc-DYKDDDDK Tag)

N° du produit ABIN2727167

Détail du produit

Antigène: Neuroligin 3 (NLGN3)

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette Neuroligin 3 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human Neuroligin 3 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Référence

Venkatesh, Johung, Caretti, Noll, Tang, Nagaraja, Gibson, Mount, Polepalli, Mitra, Woo, Malenka, Vogel, Bredel, Mallick, Monje: "Neuronal Activity Promotes Glioma Growth through Neuroligin-3 Secretion." dans: Cell, Vol. 161, Issue 4, pp. 803-16, (2015) (PubMed).

Détail du antigène

Antigène: Neuroligin 3 (NLGN3)

Autre désignation: Neuroligin 3 (NLGN3 Produits)

Synonymes: Nlgn3 Protein, GB18290 Protein, hnl3 Protein, NLGN3 Protein, CCE-L1 Protein, NV16744 Protein, Nv1604741 Protein, HNL3 Protein, A230085M13Rik Protein, NL3 Protein, neuroligin 3 Protein, neuroligin 3 S homeolog Protein, NLG-3 Protein, nlgn3.S Protein, NLGN3 Protein, LOC659852 Protein, LOC100121155 Protein, nlgn3 Protein, Nlgn3 Protein

Sujet: This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. Mutations in this gene may be associated with autism and Asperger syndrome. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

Poids moléculaire: 91.4 kDa

NCBI Accession: NP_061850

Pathways: Synaptic Membrane