ISCU Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Antigène Voir toutes ISCU Protéines
- ISCU (Iron-sulfur cluster assembly enzyme ISCU, mitochondrial (ISCU))
- Type de proteíne
- Recombinant
- Attributs du protein
- Transcript Variant 1
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette ISCU protéine est marqué à la Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Attributs du produit
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- Recombinant human ISCU / NIFUN (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Pureté
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product ISCU Protéine
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- Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Commentaires
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Stock
- -80 °C
- Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Antigène
- ISCU (Iron-sulfur cluster assembly enzyme ISCU, mitochondrial (ISCU))
- Autre désignation
- Nifun (ISCU Produits)
- Synonymes
- nifun Protein, zC191D15.3 Protein, si:ch211-191d15.3 Protein, 2310020H20Rik Protein, HML Protein, ISU2 Protein, NIFU Protein, NIFUN Protein, hnifU Protein, RGD1309562 Protein, AA407971 Protein, Nifu Protein, Nifun Protein, iron-sulfur cluster assembly enzyme ISCU, mitochondrial Protein, iron-sulfur cluster assembly enzyme Protein, iron-sulfur cluster assembly enzyme a Protein, LOC409130 Protein, ISCU Protein, iscua Protein, Iscu Protein
- Sujet
- This gene encodes a component of the iron-sulfur (Fe-S) cluster scaffold. Fe-S clusters are cofactors that play a role in the function of a diverse set of enzymes, including those that regulate metabolism, iron homeostasis, and oxidative stress response. Alternative splicing results in transcript variants encoding different protein isoforms that localize either to the cytosol or to the mitochondrion. Mutations in this gene have been found in patients with hereditary myopathy with lactic acidosis. A disease-associated mutation in an intron may activate a cryptic splice site, resulting in the production of a splice variant encoding a putatively non-functional protein. A pseudogene of this gene is present on chromosome 1.
- Poids moléculaire
- 15.1 kDa
- NCBI Accession
- NP_055116
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