Nyctalopin Protein (NYX) (Myc-DYKDDDDK Tag)

N° du produit ABIN2727840

Détail du produit

Antigène: Nyctalopin (NYX)

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette Nyctalopin protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human Nyctalopin protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: Nyctalopin (NYX)

Autre désignation: Nyctalopin (NYX Produits)

Synonymes: MGC84276 Protein, CLRP Protein, CSNB1 Protein, CSNB1A Protein, CSNB4 Protein, NBM1 Protein, CLNP Protein, nob Protein, RGD1561300 Protein, nyctalopin Protein, nyctalopin L homeolog Protein, uncharacterized LOC491837 Protein, NYX Protein, nyx.L Protein, LOC491837 Protein, nyx Protein, Nyx Protein

Sujet: The product of this gene belongs to the small leucine-rich proteoglycan (SLRP) family of proteins. Defects in this gene are the cause of congenital stationary night blindness type 1 (CSNB1), also called X-linked congenital stationary night blindness (XLCSNB). CSNB1 is a rare inherited retinal disorder characterized by impaired scotopic vision, myopia, hyperopia, nystagmus and reduced visual acuity. The role of other SLRP proteins suggests that mutations in this gene disrupt developing retinal interconnections involving the ON-bipolar cells, leading to the visual losses seen in patients with complete CSNB.

Poids moléculaire: 49.5 kDa

NCBI Accession: NP_072089