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PAK2 Protéine

PAK2 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % as determined by SDS-PAGE and Coomassie blue staining AbP, Func, PI, STD Active
N° du produit ABIN2728169
  • Antigène Voir toutes PAK2 Protéines
    PAK2 (P21-Activated Kinase 2 (PAK2))
    Type de proteíne
    Recombinant
    Activité biologique
    Active
    Origine
    Humain
    Source
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Application
    Antibody Production (AbP), Functional Studies (Func), Protein Interaction (PI), Standard (STD)
    Specificité
    Optimal preservation of protein structure, post-translational modifications and functions.
    Attributs du produit
    • Recombinant human PAK2 protein expressed in E. coli.
    • Produced with end-sequenced ORF clone
    • Tested for bioactivity.
    Pureté
    > 90 % as determined by SDS-PAGE and Coomassie blue staining
    niveau d'endotoxine
    <0.1 ng/μg of protein (<1EU/μg).
    Biological Activity Comment
    Specific activity was determined as 85,806 pmoles/min/μg, according to the Zlyte assay protocol
    Top Product
    Discover our top product PAK2 Protéine
  • Indications d'application
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Protein-protein interaction
    In vitro biochemical assays and cell-based functional assays
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    25 mM Tris-HCl pH 8.0, 150 mM NaCl, 10 % glycerol, 5 mM DTT.
    Stock
    -80 °C
    Stockage commentaire
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Antigène
    PAK2 (P21-Activated Kinase 2 (PAK2))
    Autre désignation
    Pak2 (PAK2 Produits)
    Synonymes
    PAK65 Protein, PAKgamma Protein, gamma-PAK Protein, 5330420P17Rik Protein, A130002K10Rik Protein, AI836325 Protein, D16Ertd269e Protein, PAK-2 Protein, mKIAA4182 Protein, pak2 Protein, cb422 Protein, kinase Protein, zgc:91798 Protein, wu:fb71h01 Protein, si:dz198m22.1 Protein, pak65 Protein, pakgamma Protein, PAKI Protein, Pak3 Protein, CH73-159L23.1 Protein, wu:fc52b03 Protein, zgc:113857 Protein, p21 (RAC1) activated kinase 2 Protein, p21 protein (Cdc42/Rac)-activated kinase 2 Protein, p21 protein (Cdc42/Rac)-activated kinase 2a Protein, p21 protein (Cdc42/Rac)-activated kinase 2 S homeolog Protein, p21 protein (Cdc42/Rac)-activated kinase 2b Protein, PAK2 Protein, Pak2 Protein, pak2a Protein, pak2.S Protein, pak2b Protein
    Sujet
    The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell.
    Poids moléculaire
    33.5 kDa
    NCBI Accession
    NP_002568
    Pathways
    Signalisation MAPK, Signalisation RTK, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha
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