PGPEP1 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2728797

Détail du produit

Antigène: PGPEP1 (Pyroglutamyl-Peptidase I (PGPEP1))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette PGPEP1 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human PGPEP1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: PGPEP1 (Pyroglutamyl-Peptidase I (PGPEP1))

Autre désignation: Pgpep1 (PGPEP1 Produits)

Synonymes: PGP Protein, PGP-I Protein, PGPI Protein, Pcp Protein, 2810003H13Rik Protein, Gm19458 Protein, PAP-I Protein, PAPI Protein, pyroglutamyl-peptidase I Protein, Pyroglutamyl-peptidase I Protein, Fnod_0998 Protein, Tlet_1256 Protein, Franean1_3440 Protein, Sked_37410 Protein, Arch_1014 Protein, Olsu_1567 Protein, Bcell_2984 Protein, Deima_2337 Protein, Spico_0458 Protein, Poras_1572 Protein, PGPEP1 Protein, Pgpep1 Protein

Sujet: The gene encodes a cysteine protease and member of the peptidase C15 family of proteins. The encoded protein cleaves amino terminal pyroglutamate residues from protein substrates including thyrotropin-releasing hormone and other neuropeptides. Expression of this gene may be downregulated in colorectal cancer, while activity of the encoded protein may be negatively correlated with cancer progression in colorectal cancer patients. Activity of the encoded protease may also be altered in other disease states including in liver cirrhosis, which is associated with reduced protease activity, and in necrozoospermia, which is associated with elevated protease activity.

Poids moléculaire: 23 kDa

NCBI Accession: NP_060182