PRKAG1 Protein (Catalytic Subunit, Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- Antigène Voir toutes PRKAG1 Protéines
- PRKAG1 (Protein Kinase, AMP-Activated, gamma 1 Non-Catalytic Subunit (PRKAG1))
- Type de proteíne
- Recombinant
- Attributs du protein
- Catalytic Subunit, Transcript Variant 2
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette PRKAG1 protéine est marqué à la Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Attributs du produit
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- Recombinant human Protein kinase, AMP-activated, gamma 1 non-catalytic subunit (PRKAG1), transcript variant 2 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Pureté
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PRKAG1 Protéine
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- Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Commentaires
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Stock
- -80 °C
- Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Antigène
- PRKAG1 (Protein Kinase, AMP-Activated, gamma 1 Non-Catalytic Subunit (PRKAG1))
- Abstract
- PRKAG1 Produits
- Synonymes
- MGC68503 Protein, zgc:63896 Protein, wu:fa94d09 Protein, wu:fd12h04 Protein, AMPKG Protein, Prkaac Protein, Prkga1 Protein, AA571379 Protein, BB036179 Protein, protein kinase, AMP-activated, gamma 1 non-catalytic subunit S homeolog Protein, protein kinase, AMP-activated, gamma 1 non-catalytic subunit Protein, protein kinase AMP-activated non-catalytic subunit gamma 1 Protein, prkag1.S Protein, prkag1 Protein, PRKAG1 Protein, Prkag1 Protein
- Sujet
- The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
- Poids moléculaire
- 28.1 kDa
- NCBI Accession
- NP_997626
- Pathways
- AMPK Signaling, Regulation of Carbohydrate Metabolic Process, L'effet Warburg
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