ROR1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Antigène Voir toutes ROR1 Protéines
- ROR1 (Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1))
- Type de proteíne
- Recombinant
- Attributs du protein
- Transcript Variant 1
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette ROR1 protéine est marqué à la Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Attributs du produit
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- Recombinant human ROR1 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Pureté
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product ROR1 Protéine
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- Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Commentaires
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Stock
- -80 °C
- Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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Spontaneous Immunity Against the Receptor Tyrosine Kinase ROR1 in Patients with Chronic Lymphocytic Leukemia." dans: PLoS ONE, Vol. 10, Issue 11, pp. e0142310, (2015) (PubMed).
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Spontaneous Immunity Against the Receptor Tyrosine Kinase ROR1 in Patients with Chronic Lymphocytic Leukemia." dans: PLoS ONE, Vol. 10, Issue 11, pp. e0142310, (2015) (PubMed).
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- Antigène
- ROR1 (Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1))
- Autre désignation
- Ror1 (ROR1 Produits)
- Synonymes
- NTRKR1 Protein, dJ537F10.1 Protein, 2810404D04Rik Protein, Ntrkr1 Protein, mRor1 Protein, RGD1559469 Protein, ROR1 Protein, fi34e02 Protein, si:dkey-209n16.1 Protein, wu:fi34e02 Protein, receptor tyrosine kinase like orphan receptor 1 Protein, receptor tyrosine kinase-like orphan receptor 1 Protein, ROR1 Protein, Ror1 Protein, ror1 Protein
- Sujet
- This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms.
- Poids moléculaire
- 104.1 kDa
- NCBI Accession
- NP_005003
- Pathways
- Signalisation RTK, Signalisation WNT, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha
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