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SCARB2 Protéine

SCARB2 Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
N° du produit ABIN2731449
  • Antigène Voir toutes SCARB2 Protéines
    SCARB2 (Scavenger Receptor Class B, Member 2 (SCARB2))
    Type de proteíne
    Recombinant
    Origine
    • 9
    • 4
    Humain
    Source
    • 6
    • 5
    • 2
    HEK-293 Cells
    Application
    Antibody Production (AbP), Standard (STD)
    Attributs du produit
    • Recombinant human SCARB2 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Pureté
    > 95 % as determined by SDS-PAGE and Coomassie blue staining
    niveau d'endotoxine
    < 0.1 EU per μg protein as determined by LAL test
    Top Product
    Discover our top product SCARB2 Protéine
  • Indications d'application
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Restrictions
    For Research Use only
  • Buffer
    Lyophilized from a 0.2 μM filtered solution of 20 mM Phosphate buffer, 150 mM NaCl, pH 7.2. Stable for at least 6 months from date of receipt under proper storage and handling conditions.
    Stock
    -80 °C
    Stockage commentaire
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Antigène
    SCARB2 (Scavenger Receptor Class B, Member 2 (SCARB2))
    Autre désignation
    Scarb2 (SCARB2 Produits)
    Synonymes
    cd36l2 Protein, fi13c07 Protein, chunp6914 Protein, wu:fi13c07 Protein, SCARB2 Protein, scarb2 Protein, AMRF Protein, CD36L2 Protein, EPM4 Protein, HLGP85 Protein, LGP85 Protein, LIMP-2 Protein, LIMPII Protein, SR-BII Protein, 9330185J12Rik Protein, Cd36l2 Protein, MLGP85 Protein, LimpII Protein, scavenger receptor class B, member 2a Protein, scavenger receptor class B member 2 Protein, scavenger receptor class B, member 2 Protein, scarb2a Protein, SCARB2 Protein, scarb2 Protein, Scarb2 Protein
    Sujet
    The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is a ubiquitously expressed protein and that it is involved in the pathogenesis of HFMD (hand, foot, and mouth disease) caused by enterovirus-71 and possibly by coxsackievirus A16. Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011].
    Poids moléculaire
    47.6 kDa
    NCBI Accession
    NP_005497
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