Seladin 1 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2731608

Détail du produit

Antigène: Seladin 1 (DHCR24) (24-Dehydrocholesterol Reductase (DHCR24))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette Seladin 1 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human Seladin-1 / DHCR24 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: Seladin 1 (DHCR24) (24-Dehydrocholesterol Reductase (DHCR24))

Autre désignation: Seladin-1,dhcr24 (DHCR24 Produits)

Synonymes: MGC82737 Protein, zgc:101638 Protein, DCE Protein, Nbla03646 Protein, SELADIN1 Protein, seladin-1 Protein, 2310076D10Rik Protein, 5830417J06Rik Protein, mKIAA0018 Protein, 24-dehydrocholesterol reductase Protein, 24-dehydrocholesterol reductase S homeolog Protein, delta(24)-sterol reductase Protein, DHCR24 Protein, dhcr24.S Protein, dhcr24 Protein, LOC5575872 Protein, CpipJ_CPIJ000670 Protein, Dhcr24 Protein

Sujet: This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells.

Poids moléculaire: 57.6 kDa

NCBI Accession: NP_055577