SERPINB2 Protein (Transcript Variant 2)

N° du produit ABIN2731773

Détail du produit

Antigène: SERPINB2 (Plasminogen Activator Inhibitor 2 (SERPINB2))

Type de proteíne: Recombinant

Activité biologique: Active

Attributs du protein: Transcript Variant 2

Origine: Humain

Source: Escherichia coli (E. coli)

Application: Functional Studies (Func), Antibody Production (AbP), Standard (STD), Protein Interaction (PI)

Specificité: Optimal preservation of protein structure, post-translational modifications and functions.

Attributs du produit:

• Recombinant human SERPINB2 / PAI2 (transcript variant 2) protein expressed in E. coli.
• Produced with end-sequenced ORF clone
• Tested for bioactivity.

Pureté: > 95 % as determined by SDS-PAGE and Coomassie blue staining

niveau d'endotoxine: Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).

Biological Activity Comment: Determined by its inhibitory effect against single chain tPA induced cleavage of a chromogenic substrate in Imidazole Buffer at 37C. Half maximal inhibition against 1.0 ug/mL of single chain tPA was obtained at a concentration of 1.0 ug/mL

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays

Restrictions: For Research Use only

Stockage

Buffer: Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2

Conseil sur la manipulation: Resuspend the protein in the desired concentration in proper buffer

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: SERPINB2 (Plasminogen Activator Inhibitor 2 (SERPINB2))

Autre désignation: Serpinb2,pai2 (SERPINB2 Produits)

Synonymes: HsT1201 Protein, PAI Protein, PAI-2 Protein, PAI2 Protein, PLANH2 Protein, SERPINB2 Protein, Planh2 Protein, ovalbumin Protein, Pai2a Protein, serpin family B member 2 Protein, serpin peptidase inhibitor, clade B (ovalbumin), member 2 Protein, serine (or cysteine) peptidase inhibitor, clade B, member 2 Protein, SERPINB2 Protein, Serpinb2 Protein

Classe de substances: Amino Acid

Sujet: Inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell-derived PAI-1. [UniProtKB/Swiss-Prot Function]

Poids moléculaire: 45.6 kDa

NCBI Accession: NP_002566

Pathways: Autophagy