SETMAR Protein (Myc-DYKDDDDK Tag)
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- Antigène Voir toutes SETMAR Protéines
- SETMAR (SET Domain and Mariner Transposase Fusion Gene (SETMAR))
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette SETMAR protéine est marqué à la Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Attributs du produit
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- Recombinant human SETMAR protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Pureté
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product SETMAR Protéine
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- Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Commentaires
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Stock
- -80 °C
- Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Antigène
- SETMAR (SET Domain and Mariner Transposase Fusion Gene (SETMAR))
- Autre désignation
- Setmar (SETMAR Produits)
- Synonymes
- HsMar1 Protein, METNASE Protein, Mar1 Protein, 5830404F24Rik Protein, Etet2 Protein, SETMAR Protein, zgc:172212 Protein, SET domain and mariner transposase fusion gene Protein, SET domain without mariner transposase fusion Protein, histone-lysine N-methyltransferase SETMAR Protein, SETMAR Protein, Setmar Protein, LOC470738 Protein, setmar Protein, LOC703880 Protein, LOC100447656 Protein, LOC100586616 Protein
- Sujet
- This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants.
- Poids moléculaire
- 77.9 kDa
- NCBI Accession
- NP_006506
- Pathways
- Positive Regulation of Response to DNA Damage Stimulus
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