SNAPIN Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2732314

Détail du produit

Antigène: SNAPIN (SNAP-Associated Protein (SNAPIN))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette SNAPIN protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human SNAPIN protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: SNAPIN (SNAP-Associated Protein (SNAPIN))

Autre désignation: Snapin (SNAPIN Produits)

Synonymes: SNAPAP Protein, si:dkey-222b8.2 Protein, SNAPIN Protein, BLOC1S7 Protein, BLOS7 Protein, 25kDa Protein, AA407989 Protein, AV026596 Protein, Bloc1s7 Protein, Snap25bp Protein, Snapap Protein, SNAP associated protein Protein, SNAP-associated protein L homeolog Protein, SNAP-associated protein Protein, SNAPIN Protein, snapin.L Protein, snapin Protein, Snapin Protein

Sujet: The protein encoded by this gene is a coiled-coil-forming protein that associates with the SNARE (soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor) complex of proteins and the BLOC-1 (biogenesis of lysosome-related organelles) complex. Biochemical studies have identified additional binding partners. As part of the SNARE complex, it is required for vesicle docking and fusion and regulates neurotransmitter release. The BLOC-1 complex is required for the biogenesis of specialized organelles such as melanosomes and platelet dense granules. Mutations in gene products that form the BLOC-1 complex have been identified in mouse strains that are models of Hermansky-Pudlak syndrome. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 14.7 kDa

NCBI Accession: NP_036569

Pathways: Synaptic Membrane, Synaptic Vesicle Exocytosis