TGFB1 Protein (Myc-DYKDDDDK Tag)
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- Antigène Voir toutes TGFB1 Protéines
- TGFB1 (Transforming Growth Factor, beta 1 (TGFB1))
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette TGFB1 protéine est marqué à la Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Attributs du produit
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- Recombinant human TGFB1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Pureté
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product TGFB1 Protéine
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- Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Commentaires
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Stock
- -80 °C
- Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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Oxidative stress is responsible for maternal diabetes-impaired transforming growth factor beta signaling in the developing mouse heart." dans: American journal of obstetrics and gynecology, Vol. 212, Issue 5, pp. 650.e1-11, (2015) (PubMed).
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Oxidative stress is responsible for maternal diabetes-impaired transforming growth factor beta signaling in the developing mouse heart." dans: American journal of obstetrics and gynecology, Vol. 212, Issue 5, pp. 650.e1-11, (2015) (PubMed).
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- Antigène
- TGFB1 (Transforming Growth Factor, beta 1 (TGFB1))
- Autre désignation
- Tgfb1 (TGFB1 Produits)
- Synonymes
- CED Protein, DPD1 Protein, LAP Protein, TGFB Protein, TGFbeta Protein, TGF-beta Protein, TGF-BETA-1 Protein, TGF-beta5 Protein, ced Protein, dpd1 Protein, lap Protein, tgf-beta Protein, tgfb Protein, tgfb5 Protein, tgfbeta Protein, TGF-beta1 Protein, TGFbeta1 Protein, Tgfb Protein, Tgfb-1 Protein, ai39657 Protein, tgfb1 Protein, wu:fb13a07 Protein, xx:ai39657 Protein, TGFB1 Protein, csd Protein, cdb1 Protein, cdg2 Protein, csd1 Protein, csd2 Protein, csd3 Protein, ebmd Protein, lcd1 Protein, bigh3 Protein, cdgg1 Protein, betaig-h3 Protein, TGFB4 Protein, transforming growth factor beta 1 Protein, transforming growth factor beta-1 Protein, transforming growth factor beta 1 L homeolog Protein, transforming growth factor, beta 1 Protein, transforming growth factor, beta 1a Protein, transforming growth factor beta induced L homeolog Protein, TGFB1 Protein, Tgfb1 Protein, tgfb1.L Protein, tgfb1a Protein, tgfbi.L Protein
- Sujet
- This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGFB family members. This encoded protein regulates cell proliferation, differentiation and growth, and can modulate expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.
- Poids moléculaire
- 28.4 kDa
- NCBI Accession
- NP_000651
- Pathways
- EGFR Signaling Pathway, Dopaminergic Neurogenesis, Cellular Response to Molecule of Bacterial Origin, Glycosaminoglycan Metabolic Process, Regulation of Leukocyte Mediated Immunity, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Ribonucleoside Biosynthetic Process, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy, Cancer Immune Checkpoints
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