TGIF1 Protein (His tag)
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- Antigène Voir toutes TGIF1 Protéines
- TGIF1 (TGFB-Induced Factor Homeobox 1 (TGIF1))
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette TGIF1 protéine est marqué à la His tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Attributs du produit
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- Recombinant human TGIF1 (full length, N-term HIS tag, transcript variant 4) protein expressed in E.coli.
- Produced with end-sequenced ORF clone
- Pureté
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product TGIF1 Protéine
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- Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Commentaires
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The tag is located at the N-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.
- Stock
- -80 °C
- Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Antigène
- TGIF1 (TGFB-Induced Factor Homeobox 1 (TGIF1))
- Autre désignation
- Tgif1 (TGIF1 Produits)
- Synonymes
- HPE4 Protein, TGIF Protein, AA959811 Protein, AI462167 Protein, Tgif Protein, Tfig Protein, fa06h05 Protein, fb33g11 Protein, zgc:55852 Protein, wu:fa06h05 Protein, wu:fb33g11 Protein, hpe4 Protein, tgif Protein, tgif1 Protein, TGFB induced factor homeobox 1 Protein, TGFB-induced factor homeobox 1 Protein, TGFB induced factor homeobox 1 S homeolog Protein, TGIF1 Protein, Tgif1 Protein, tgif1 Protein, tgif1.S Protein
- Sujet
- The protein encoded by this gene is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain. Alternative splicing has been observed at this locus and multiple splice variants encoding distinct isoforms are described.
- Poids moléculaire
- 29.6 kDa
- NCBI Accession
- NP_003235
- Pathways
- Retinoic Acid Receptor Signaling Pathway, Chromatin Binding, Tube Formation
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