TYMS Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2733654

Détail du produit

Antigène: TYMS (Thymidylate Synthetase (TYMS))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette TYMS protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human Thymidylate synthase (TS) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: TYMS (Thymidylate Synthetase (TYMS))

Autre désignation: Thymidylate Synthase (Ts) (TYMS Produits)

Synonymes: FN1 Protein, ECK2823 Protein, JW2795 Protein, ts Protein, Ts Protein, HST422 Protein, TMS Protein, TS Protein, thymidylate synthetase Protein, contains intron in T4 phage Protein, ThyE Protein, thymidylate synthase Protein, thymidylate synthetase L homeolog Protein, TYMS Protein, thyA Protein, td Protein, thyE Protein, DDA3937_RS04960 Protein, tyms.L Protein, XBJ1_RS15770 Protein, EAMY_RS20680 Protein, Tyms Protein

Classe de substances: Viral Protein

Sujet: Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs. Expression of this gene and that of a naturally occuring antisense transcript rTSalpha (GeneID:55556) vary inversely when cell-growth progresses from late-log to plateau phase.

Poids moléculaire: 35.5 kDa

NCBI Accession: NP_001062

Pathways: Mitotic G1-G1/S Phases