TIE1 Protein (DYKDDDDK-His Tag)
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- Antigène Voir toutes TIE1 Protéines
- TIE1 (tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1))
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette TIE1 protéine est marqué à la DYKDDDDK-His Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Attributs du produit
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- Recombinant human TIE1 (C-term DDK/His tag) protein expressed in Human 293HEK cells.
- Produced with end-sequenced ORF clone
- Pureté
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product TIE1 Protéine
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- Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Commentaires
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 1 x PBS, pH 7.4, 10 % glycerol.
- Stock
- -80 °C
- Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Antigène
- TIE1 (tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1))
- Autre désignation
- Tie1 (TIE1 Produits)
- Synonymes
- JTK14 Protein, TIE Protein, D430008P04Rik Protein, tie-1 Protein, tyrosine kinase with immunoglobulin like and EGF like domains 1 Protein, tyrosine kinase with immunoglobulin-like and EGF-like domains 1 Protein, tyrosine-protein kinase receptor Tie-1 Protein, endothelium-specific receptor tyrosine kinase 1 Protein, TIE1 Protein, Tie1 Protein, CpipJ_CPIJ018933 Protein, tie1 Protein
- Sujet
- This gene encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
- Poids moléculaire
- 82.6 kDa
- NCBI Accession
- NP_005415
- Pathways
- Signalisation RTK
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