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Mps1 Protein (TTK) (Myc-DYKDDDDK Tag)

TTK Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
N° du produit ABIN2734513
  • Antigène Voir toutes Mps1 (TTK) Protéines
    Mps1 (TTK)
    Type de proteíne
    Recombinant
    Origine
    • 5
    • 2
    • 2
    Humain
    Source
    • 4
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette Mps1 protéine est marqué à la Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Attributs du produit
    • Recombinant human TTK protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Pureté
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product TTK Protéine
  • Indications d'application
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Commentaires

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Stock
    -80 °C
    Stockage commentaire
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Antigène
    Mps1 (TTK)
    Autre désignation
    Ttk (TTK Produits)
    Synonymes
    CT96 Protein, ESK Protein, MPH1 Protein, MPS1 Protein, MPS1L1 Protein, PYT Protein, AL022661 Protein, Esk1 Protein, Mps1 Protein, esk Protein, mps1 Protein, ncp Protein, Ttk protein kinase Protein, TTK protein kinase Protein, ttk protein kinase Protein, Ttk Protein, TTK Protein, ttk Protein
    Sujet
    This gene encodes a dual specificity protein kinase with the ability to phosphorylate tyrosine, serine and threonine. Associated with cell proliferation, this protein is essential for chromosome alignment at the centromere during mitosis and is required for centrosome duplication. It has been found to be a critical mitotic checkpoint protein for accurate segregation of chromosomes during mitosis. Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles. Alternative splicing results in multiple transcript variants.
    Poids moléculaire
    96.9 kDa
    NCBI Accession
    NP_003309
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