VAC14 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2735160

Détail du produit

Antigène: VAC14 (Vac14 Homolog (VAC14))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette VAC14 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human VAC14 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: VAC14 (Vac14 Homolog (VAC14))

Autre désignation: Vac14 (VAC14 Produits)

Synonymes: ArPIKfyve Protein, TAX1BP2 Protein, TRX Protein, AA959718 Protein, BC032215 Protein, D8Wsu151e Protein, Tax1bp2 Protein, Trx Protein, ingls Protein, Vac14 homolog L homeolog Protein, Vac14, PIKFYVE complex component Protein, Vac14 homolog (S. cerevisiae) Protein, vac14.L Protein, VAC14 Protein, Vac14 Protein

Sujet: The content of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) in endosomal membranes changes dynamically with fission and fusion events that generate or absorb intracellular transport vesicles. VAC14 is a component of a trimolecular complex that tightly regulates the level of PtdIns(3,5)P2. Other components of this complex are the PtdIns(3,5)P2-synthesizing enzyme PIKFYVE (MIM 609414) and the PtdIns(3,5)P2 phosphatase FIG4 (MIM 609390). VAC14 functions as an activator of PIKFYVE (Sbrissa et al., 2007 [PubMed 17556371]).[supplied by OMIM, Feb 2010]

Poids moléculaire: 87.8 kDa

NCBI Accession: NP_060522

Pathways: Inositol Metabolic Process