ZAP70 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Antigène Voir toutes ZAP70 Protéines
- ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))
- Type de proteíne
- Recombinant
- Attributs du protein
- Transcript Variant 1
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette ZAP70 protéine est marqué à la Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Attributs du produit
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- Recombinant human ZAP70 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Pureté
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product ZAP70 Protéine
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- Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Commentaires
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Stock
- -80 °C
- Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Antigène
- ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))
- Autre désignation
- Zap70 (ZAP70 Produits)
- Synonymes
- SRK Protein, STCD Protein, STD Protein, TZK Protein, ZAP-70 Protein, 70kDa Protein, AI327364 Protein, Srk Protein, mrtle Protein, mur Protein, zap70 Protein, MGC80670 Protein, MGC88962 Protein, ZAP70 Protein, zgc:110383 Protein, zeta chain of T-cell receptor associated protein kinase 70 Protein, putative tyrosine-protein kinase zap-70 Protein, zeta-chain (TCR) associated protein kinase Protein, zeta chain of T cell receptor associated protein kinase 70 Protein, zeta-chain (TCR) associated protein kinase 70kDa Protein, zeta chain of T cell receptor associated protein kinase 70kDa L homeolog Protein, zeta chain of T cell receptor associated protein kinase 70kDa Protein, tyrosine-protein kinase ZAP-70 Protein, ZAP70 Protein, Smp_149470 Protein, Zap70 Protein, zap70.L Protein, zap70 Protein, LOC707555 Protein, LOC100342021 Protein, LOC100390922 Protein, LOC100542877 Protein
- Sujet
- This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.
- Poids moléculaire
- 69.7 kDa
- NCBI Accession
- NP_001070
- Pathways
- TCR Signaling, Ubiquitin Proteasome Pathway
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