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DLK1 Protein (AA 24-303, Extracellular Domain) (Fc Tag)

DLK1 Origine: Humain Hôte: HEK-293 Cells Recombinant >90 % (SDS-PAGE) SDS Active
N° du produit ABIN2745649
  • Antigène Voir toutes DLK1 Protéines
    DLK1 (delta-Like 1 Homolog (Drosophila) (DLK1))
    Type de proteíne
    Recombinant
    Activité biologique
    Active
    Attributs du protein
    Extracellular Domain, AA 24-303
    Origine
    • 13
    • 4
    • 1
    • 1
    Humain
    Source
    • 8
    • 8
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette DLK1 protéine est marqué à la Fc Tag.
    Application
    SDS-PAGE (SDS)
     Réactivité croisée
    Humain
    Attributs du produit
    Signal peptide and extracellular domain of human DLK1 (aa 24-303) are fused at the C-terminus to the Fc portion of human IgG1.
    Pureté
    >90 % (SDS-PAGE)
    niveau d'endotoxine
    <0.01EU/μg purified protein (LAL test, Lonza).
    Top Product
    Discover our top product DLK1 Protéine
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Commentaires

    Inhibits adipogenesis of 3T3L-1 cells.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute with 100 μL sterile water.
    Concentration
    Lot specific
    Buffer
    Lyophilized. Contains PBS + 0.02 % CHAPS.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 6 months after receipt when stored at -20°C.
    Date de péremption
    6 months
  • Antigène
    DLK1 (delta-Like 1 Homolog (Drosophila) (DLK1))
    Autre désignation
    DLK1 (DLK1 Produits)
    Synonymes
    DELTA1 Protein, DL1 Protein, Delta Protein, DLK Protein, DLK-1 Protein, Delta1 Protein, FA1 Protein, PREF1 Protein, Pref-1 Protein, ZOG Protein, pG2 Protein, AW742678 Protein, DlkI Protein, Ly107 Protein, Peg9 Protein, SCP1 Protein, pref-1 Protein, Zog Protein, delta like canonical Notch ligand 1 Protein, delta like non-canonical Notch ligand 1 Protein, delta-like 1 homolog (Drosophila) Protein, delta-like 1 (Drosophila) Protein, DLL1 Protein, DLK1 Protein, Dll1 Protein, Dlk1 Protein
    Sujet
    The transmembrane and secreted protein delta-like 1 homolog (DLK1, Protein delta homolog 1, Preadipocyte factor 1, Pref-1) belongs to the EGF-like family. It can be cleaved by a tumor necrosis factor-alpha converting enzyme (TACE) to release a soluble form. DLK1 plays important roles in regulating cell differentiation such as adipogenesis and osteogenesis. Membrane-bound DLK1 promotes hypertrophic myotube formation, whereas soluble DLK1 inhibits myotube formation. The soluble form of DLK1 inhibits preadipocyte differentiation, while membrane DLK1 represses preadipocyte proliferation. DLK1 is also associated with tumor invasion.
    Poids moléculaire
    ~65kDa (SDS-PAGE)
    UniProt
    P80370
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