IGFBP7
(Insulin-Like Growth Factor Binding Protein 7 (IGFBP7))
Type de proteíne
Recombinant
Attributs du protein
AA 30-282
Origine
Humain
Source
HEK-293 Cells
Purification/Conjugué
Cette IGFBP7 protéine est marqué à la His tag.
Séquence
AA 30-282
Attributs du produit
This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 27 kDa. The protein migrates as 35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
IGFBP7
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Insulin-like growth factor-binding protein 7 (IGFBP7) is also known as IGFBP-rP1, MAC25 protein, PGI2-stimulating factor, prostacyclin-stimulating factor and tumor-derived adhesion factor, which contains one Ig-like C2-type (immunoglobulin-like) domain, one IGFBP N-terminal domain and one Kazal-like domain. The major function of IGFBP7 is the regulation of availability of insulin-like growth factors (IGFs) in tissue as well as in modulating IGF binding to its receptors. IGFBP7 binds to IGF with high affinity except for IGF-I and IGF-II.IGFBP7 also stimulates cell adhesion. Furthermore, IGFBP7 is implicated in some cancers.