VTCN1
(V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1))
Type de proteíne
Recombinant
Activité biologique
Active
Attributs du protein
AA 33-194
Origine
Humain
Source
HEK-293 Cells
Purification/Conjugué
Cette VTCN1 protéine est marqué à la Fc Tag.
Séquence
AA 33-194
Attributs du produit
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 44.8 kDa. The protein migrates as 55-60 kDa under reducing (R) condition (SDS-PAGE) due to Glycosylation.
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Sujet
Platelet receptor Gi24, also known as B7-H5 and stress-induced secreted protein-1 (Sisp-1), is a protein that in humans is encoded by the C10orf54 gene, which contains 1 Ig-like (immunoglobulin-like) domain. As for C10orf54 gene, C10orf54 appears to positively interact with BMP-4, potentiating BMP signaling and the transition from an undifferentiated to a differentiated state on ESCs. Human C10orf54 undergoes proteolytic cleavage by MT1-MMP, generating a soluble 30 kDa extracellular fragment plus a 25-30 kDa membrane-bound fragment.