CX3CL1 Protein (AA 25-341) (His tag,Biotin)
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- Antigène Voir toutes CX3CL1 Protéines
- CX3CL1 (Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 25-341
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette CX3CL1 protéine est marqué à la His tag,Biotin.
- Application
- Functional Studies (Func)
- Marque
- MABSol®,PrecisionAvi
- Séquence
- AA 25-341
- Specificité
- The primary amines in the side chains of lysine residues and the N-terminus of the protein are conjugated with biotins using standard chemical labeling method. A standard biotin reagent (13.5 angstroms) is used in this product.
- Attributs du produit
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 35.5 kDa. The protein migrates as 50-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Pureté
- >95 % as determined by SDS-PAGE.
- niveau d'endotoxine
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product CX3CL1 Protéine
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- Commentaires
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A chemically labeled biotinylated protein with ultra sensitivity.
The product is produced using a chemical labeling approach. The primary amines in the side chains of lysine residues and the N-terminus of protein are conjugated with biotins.
Chemical labeling usually results in multiple biotin attachment on a single protein molecule, which could potentially lead to higher detection sensitivity. - Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Conseil sur la manipulation
- Please avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
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- Antigène
- CX3CL1 (Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1))
- Autre désignation
- CX3CL1 (CX3CL1 Produits)
- Synonymes
- ABCD3 Protein, CX3CL1 Protein, DKFZp459K117 Protein, Cx3c Protein, Scyd1 Protein, ABCD-3 Protein, C3Xkine Protein, CXC3 Protein, CXC3C Protein, NTN Protein, NTT Protein, SCYD1 Protein, fractalkine Protein, neurotactin Protein, AB030188 Protein, AI848747 Protein, CX3C Protein, Cxc3 Protein, D8Bwg0439e Protein, ATP binding cassette subfamily D member 3 Protein, C-X3-C motif chemokine ligand 1 Protein, chemokine (C-X3-C motif) ligand 1 Protein, ABCD3 Protein, CX3CL1 Protein, Cx3cl1 Protein, Abcd3 Protein
- Sujet
- Fractalkine is also known as C-X3-C motif chemokine 1 (CX3CL1) and neurotactin. Fractalkine is a large cytokine protein of 373 amino acids, it contains multiple domains and is the only known member of the CX3C chemokine family. Fractalkine is found commonly throughout the brain, particularly in neural cells, and its receptor is known to be present on microglial cells. It has also been found to be essential for microglial cell migration. CX3CL1 is also up-regulated in the hippocampus during a brief temporal window following spatial learning, the purpose of which may be to regulate glutamate-mediated neurotransmission tone. This indicates a possible role for the chemokine in the protective plasticity process of synaptic scaling.
- Poids moléculaire
- 35.5 kDa
- Pathways
- Synaptic Membrane
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