BTN1A1
(Butyrophilin, Subfamily 1, Member A1 (BTN1A1))
Type de proteíne
Recombinant
Attributs du protein
AA 27-242
Origine
Humain
Source
HEK-293 Cells
Purification/Conjugué
Cette BTN1A1 protéine est marqué à la His tag.
Application
Functional Studies (Func)
Séquence
AA 27-242
Attributs du produit
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 25.8 kDa. The protein migrates as 35-40 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Butyrophilin subfamily 1 member A1 (BTN1A1) is also known as BTN, which is a member of the immunoglobulin superfamily and the major protein associated with fat droplets in the milk. BTN1A1 may have a cell surface receptor function. The human butyrophilin gene is localized in the major histocompatibility complex (MHC) class I region of 6p and may have arisen relatively recently in evolution by the shuffling of exons between 2 ancestral gene families. Furthermore, BTN1A1 regulates the amount of lipids and size of droplets expressed in milk and inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion.