Biliverdin Reductase Protein (full length)

N° du produit ABIN5021775

Détail du produit

Antigène: Biliverdin Reductase (BLVRA) (Biliverdin Reductase A (BLVRA))

Type de proteíne: Native

Attributs du protein: full length

Origine: Rat

Source: Rat

Application: SDS-PAGE (SDS), Western Blotting (WB)

Séquence: MDAEPKRKFG VVVVGVGRAG SVRLRDLKDP RSAAFLNLIG FVSRRELGSL DEVRQISLED ALRSQEIDVA YICSESSSHE DYIRQFLQAG KHVLVEYPMT LSFAAAQELW ELAAQKGRVL HEEHVELLME EFEFLRREVL GKELLKGSLR FTASPLEEER FGFPAFSGIS RLTWLVSLFG ELSLISATLE ERKEDQYMKM TVQLETQNKG LLSWIEEKGP GLKRNRYVNF QFTSGSLEEV PSVGVNKNIF LKDQDIFVQK LLDQVSAEDL AAEKKRIMHC LGLASDIQKL CHQKK

Specificité: ~36 kDa

Purification: Ion-exchange Purified

Pureté: >90% pure using SDSPAGE analysis.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

This product has been certified >90% pure using SDSPAGE analysis.

Restrictions: For Research Use only

Stockage

Concentration: Lot specific

Buffer: 10 mM Tris pH 7.5, 0.1 mM EDTA, 0.2 mM DTT, 20 % glycerol

Stock: -80 °C

Détail du antigène

Antigène: Biliverdin Reductase (BLVRA) (Biliverdin Reductase A (BLVRA))

Autre désignation: BVR (BLVRA Produits)

Synonymes: blvra Protein, MGC69310 Protein, BLVRA Protein, zgc:153046 Protein, BVR Protein, Dmel\\CG9471 Protein, BLVR Protein, BVRA Protein, 0610006A11Rik Protein, 2500001N03Rik Protein, Blvr Protein, biliverdin reductase A Protein, biliverdin reductase A L homeolog Protein, CG9471 gene product from transcript CG9471-RA Protein, BLVRA Protein, blvra Protein, blvra.L Protein, CG9471 Protein, Blvra Protein

Sujet: Biliverdin Reductase (BVR) is a cytoplasmic enzyme that catalyzes the conversion of biliverdin to bilirubin by converting a double bond between the second and third pyrrole ring into a single bond (1). It is ubiqutiously expressed in all tissues- it occurs in cells and brain regiuons that already display HO-1 and HO-2, but also in regions and cell types with potential to induce stress proteins. It is unique among all enzymes in having two pH optima, using a different cofactor at each pH range, NADH at pH 7.0 and NADPH at pH 8.7 (2). It is not inactivated by heat shock, and have shown to abate inflammation, oxidative stress and apoptosis (3).

ID gène: 116599

NCBI Accession: NP_446302

UniProt: P46844