INHBB Protéine

N° du produit ABIN5505690

Détail du produit

Antigène: INHBB (Inhibin, beta B (INHBB))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: Hi-5 Cells

Application: Protein Interaction (PI), Standard (STD), Antibody Production (AbP), Functional Studies (Func)

Specificité: Optimal preservation of protein structure, post-translational modifications and functions.

Attributs du produit:

• Recombinant human Inhibin beta B chain (INHBB) protein expressed in Hi-5 insect cells.
• Produced with end-sequenced ORF clone
• Tested for bioactivity.

Pureté: > 95 % as determined by SDS-PAGE and Coomassie blue staining

niveau d'endotoxine: Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).

Biological Activity Comment: ED50 was determined by its ability to inhibit the proliferation of murine MPC-11 cells is less than or equal to 2.0 ng/ml, corresponding to a specific activity of > 5 x 10^5 units/mg.

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays

Restrictions: For Research Use only

Stockage

Buffer: Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2

Conseil sur la manipulation: Resuspend the protein in the desired concentration in proper buffer

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: INHBB (Inhibin, beta B (INHBB))

Autre désignation: Inhibin beta B chain (INHBB) (INHBB Produits)

Synonymes: actbb Protein, actbetaB Protein, inhibin Protein, inhibin, beta B Protein, inhibin beta B L homeolog Protein, inhibin beta B subunit Protein, inhibin beta B Protein, inhibin beta-B Protein, inhibin beta B chain Protein, inhbb Protein, inhbb.L Protein, INHBB Protein, Inhbb Protein, LOC100719829 Protein

Sujet: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. [UniProtKB/Swiss-Prot Function]

Poids moléculaire: 25.6 kDa

NCBI Accession: NP_002184

Pathways: Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion