FASL Protein (AA 18-111) (DYKDDDDK Tag)
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- Antigène Voir toutes FASL Protéines
- FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
- Attributs du protein
- AA 18-111
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Origine
- Humain, Souris
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette FASL protéine est marqué à la DYKDDDDK Tag.
- Application
- SDS-PAGE (SDS)
- Specificité
- Binds to human and mouse Fas.
- Réactivité croisée
- Humain, Souris
- Attributs du produit
- Human FasL (aa 139-281) is fused at the N-terminus to mouse ACRP30headless (aa 18-111) and a FLAG®-tag.
- Pureté
- >95 % (SDS-PAGE)
- niveau d'endotoxine
- <0.02EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product FASL Protéine
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Commentaires
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Induces apoptosis of human Jurkat T cells at a concentration of <0.2ng/ml.
- Restrictions
- For Research Use only
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- Format
- Solid
- Concentration
- Lot specific
- Buffer
- Lyophilized. Contains PBS.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - Date de péremption
- 6 months
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- Antigène
- FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))
- Autre désignation
- FasL (FASL Produits)
- Synonymes
- ALPS1B Protein, APT1LG1 Protein, APTL Protein, CD178 Protein, CD95-L Protein, CD95L Protein, FASL Protein, TNFSF6 Protein, fasl Protein, Fas-L Protein, Faslg Protein, Tnfsf6 Protein, gld Protein, Apt1Lg1 Protein, Fasl Protein, FASLG Protein, zgc:162027 Protein, Fas ligand Protein, Fas ligand L homeolog Protein, Fas ligand (TNF superfamily, member 6) Protein, FASLG Protein, faslg.L Protein, Fasl Protein, Faslg Protein, faslg Protein
- Sujet
- MultimericFasL™ is a high activity construct in which two trimeric FasL are artificially linked via the collagen domain of ACRP30. This construct very effectively mimics the natural membrane-assisted aggregation of FasL in vivo. FasL is a cytokine that binds to TNFRSF6/Fas, a receptor that transduces the apoptotic signal into cells. It is involved in cytotoxic T cell mediated apoptosis and in T cell development.
- Poids moléculaire
- ~40kDa (SDS-PAGE)
- UniProt
- P48023
- Pathways
- Apoptose, EGFR Signaling Pathway, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
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