IL-37 Protein (partial) (His tag)
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- Antigène Voir toutes IL-37 (IL37) Protéines
- IL-37 (IL37) (Interleukin 37 (IL37))
- Type de proteíne
- Recombinant
- Attributs du protein
- partial
- Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette IL-37 protéine est marqué à la His tag.
- Application
- Western Blotting (WB)
- Séquence
- Val 46 - Asp 218
- Pureté
- >95 % as determined by SDS-PAGE.
- niveau d'endotoxine
- Endotoxin level is less than 1.0 EU per ug by the LAL method.
- Top Product
- Discover our top product IL37 Protéine
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- Indications d'application
- This recombinant protein can be used for WB.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C.
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- Antigène
- IL-37 (IL37) (Interleukin 37 (IL37))
- Autre désignation
- IL-37 (IL37 Produits)
- Synonymes
- FIL1 Protein, FIL1(ZETA) Protein, FIL1Z Protein, IL-1F7 Protein, IL-1H Protein, IL-1H4 Protein, IL-1RP1 Protein, IL-37 Protein, IL1F7 Protein, IL1H4 Protein, IL1RP1 Protein, interleukin 37 Protein, IL37 Protein
- Sujet
- Interleukin-1 family member 7 (IL1F7b) ,a member of the IL-1 family, is aslo known as interleukin-37, interleukin-1 homolog 4 (IL-1H4), interleukin-1 zeta (IL-1 zeta) and interleukin-1-related protein, which can interact with SMAD3 and bind to IL18R1, but not to IL1R1, with lower affinity than IL18. IL1F7b is a suppressor of innate inflammatory and immune responses involved in curbing excessive inflammation. This function requires SMAD3. Therefore,IL1F7b can suppress, or reduce, proinflammatory cytokine production, including IL1A and IL6, as well as CCL12, CSF1, CSF2, CXCL13, IL1B, IL23A and IL1RN, but spare anti-inflammatory cytokines. Furthermore,IL1F7b can also inhibit dendritic cell activation.
- Poids moléculaire
- 20.3 kDa
- ID gène
- 27178
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