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BIM Protein (AA 1-198, full length) (His-SUMO Tag)

BCL2L11 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % SDS
N° du produit ABIN5709129
  • Antigène Voir toutes BIM (BCL2L11) Protéines
    BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 1-198, full length
    Origine
    • 7
    • 1
    • 1
    Humain
    Source
    • 3
    • 2
    • 2
    • 2
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette BIM protéine est marqué à la His-SUMO Tag.
    Application
    SDS-PAGE (SDS)
    Séquence
    MAKQPSDVSS ECDREGRQLQ PAERPPQLRP GAPTSLQTEP QGNPEGNHGG EGDSCPHGSP QGPLAPPASP GPFATRSPLF IFMRRSSLLS RSSSGYFSFD TDRSPAPMSC DKSTQTPSPP CQAFNHYLSA MASMRQAEPA DMRPEIWIAQ ELRRIGDEFN AYYARRVFLN NYQAAEDHPR MVILRLLRYI VRLVWRMH
    Purification
    SDS-PAGE
    Pureté
    > 90 %
    Top Product
    Discover our top product BCL2L11 Protéine
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Stock
    -80 °C,4 °C,-20 °C
    Stockage commentaire
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Antigène
    BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))
    Autre désignation
    B2L11 (BCL2L11 Produits)
    Synonymes
    bim Protein, BAM Protein, BIM Protein, BOD Protein, 1500006F24Rik Protein, Bim Protein, Bod Protein, BimL Protein, BIMEL Protein, BCL2-like 11 Protein, BCL2 like 11 Protein, BCL2-like 11 (apoptosis facilitator) Protein, bcl2l11 Protein, BCL2L11 Protein, Bcl2l11 Protein
    Sujet
    Induces apoptosis and anoikis. Isoform BimL is more potent than isoform BimEL. Isoform Bim-alpha1, isoform Bim-alpha2 and isoform Bim-alpha3 induce apoptosis, although less potent than isoform BimEL, isoform BimL and isoform BimS. Isoform Bim-gamma induces apoptosis. Isoform Bim-alpha3 induces apoptosis possibly through a caspase-mediated pathway. Isoform BimAC and isoform BimABC lack the ability to induce apoptosis.
    Poids moléculaire
    38.17 kDa
    UniProt
    O43521
    Pathways
    Signalisation PI3K-Akt, Neurotrophin Signaling Pathway, Tube Formation, Positive Regulation of Endopeptidase Activity
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