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CD44 Protein (CD44) (AA 21-606, Extracellular, Isoform 4) (His-SUMO Tag)

CD44 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % SDS
N° du produit ABIN5709235
  • Antigène Voir toutes CD44 Protéines
    CD44
    Type de proteíne
    Recombinant
    Attributs du protein
    Extracellular, Isoform 4, AA 21-606
    Origine
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Source
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette CD44 protéine est marqué à la His-SUMO Tag.
    Application
    SDS-PAGE (SDS)
    Séquence
    QIDLNITCRF AGVFHVEKNG RYSISRTEAA DLCKAFNSTL PTMAQMEKAL SIGFETCRYG FIEGHVVIPR IHPNSICAAN NTGVYILTSN TSQYDTYCFN ASAPPEEDCT SVTDLPNAFD GPITITIVNR DGTRYVQKGE YRTNPEDIYP SNPTDDDVSS GSSSERSSTS GGYIFYTFST VHPIPDEDSP WITDSTDRIP ATSTSSNTIS AGWEPNEENE DERDRHLSFS GSGIDDDEDF ISSTISTTPR AFDHTKQNQD WTQWNPSHSN PEVLLQTTTR MTDVDRNGTT AYEGNWNPEA HPPLIHHEHH EEEETPHSTS TIQATPSSTT EETATQKEQW FGNRWHEGYR QTPREDSHST TGTAAASAHT SHPMQGRTTP SPEDSSWTDF FNPISHPMGR GHQAGRRMDM DSSHSTTLQP TANPNTGLVE DLDRTGPLSM TTQQSNSQSF STSHEGLEED KDHPTTSTLT SSNRNDVTGG RRDPNHSEGS TTLLEGYTSH YPHTKESRTF IPVTSAKTGS FGVTAVTVGD SNSNVNRSLS GDQDTFHPSG GSHTTHGSES DGHSHGSQEG GANTTSGPIR TPQIPE
    Purification
    SDS-PAGE
    Pureté
    > 90 %
    Top Product
    Discover our top product CD44 Protéine
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Stock
    -80 °C,4 °C,-20 °C
    Stockage commentaire
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Antigène
    CD44
    Autre désignation
    CD44 (CD44 Produits)
    Synonymes
    CDW44 Protein, CSPG8 Protein, ECMR-III Protein, HCELL Protein, HUTCH-I Protein, IN Protein, LHR Protein, MC56 Protein, MDU2 Protein, MDU3 Protein, MIC4 Protein, Pgp1 Protein, AU023126 Protein, AW121933 Protein, AW146109 Protein, HERMES Protein, Ly-24 Protein, Pgp-1 Protein, CD44A Protein, METAA Protein, RHAMM Protein, XCD44 Protein, cd44 Protein, cdw44 Protein, cspg8 Protein, ecmr-iii Protein, hcell Protein, lhr Protein, mc56 Protein, mdu2 Protein, mdu3 Protein, mic4 Protein, mutch-i Protein, pgp1 Protein, CD44 molecule (Indian blood group) Protein, syndecan 4 Protein, CD44 antigen Protein, CD44 molecule (Indian blood group) S homeolog Protein, CD44 Protein, SDC4 Protein, Cd44 Protein, cd44.S Protein
    Sujet
    Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. In cancer cells, may play an important role in invadopodia formation. Also involved in lymphocyte activation, recirculation and homing, and in hatopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events.
    Poids moléculaire
    80.1 kDa
    UniProt
    P16070
    Pathways
    Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
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