Id2 Protein (AA 1-134, full length) (His-SUMO Tag)
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- Antigène Voir toutes Id2 Protéines
- Id2 (Inhibitor of DNA Binding 2 (Id2))
- Type de proteíne
- Recombinant
- Attributs du protein
- full length, AA 1-134
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette Id2 protéine est marqué à la His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Séquence
- MKAFSPVRSV RKNSLSDHSL GISRSKTPVD DPMSLLYNMN DCYSKLKELV PSIPQNKKVS KMEILQHVID YILDLQIALD SHPTIVSLHH QRPGQNQASR TPLTTLNTDI SILSLQASEF PSELMSNDSK ALCG
- Purification
- SDS-PAGE
- Pureté
- > 90 %
- Top Product
- Discover our top product Id2 Protéine
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Stock
- -80 °C,4 °C,-20 °C
- Stockage commentaire
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Antigène
- Id2 (Inhibitor of DNA Binding 2 (Id2))
- Autre désignation
- ID2 (Id2 Produits)
- Synonymes
- AI255428 Protein, C78922 Protein, Idb2 Protein, bHLHb26 Protein, Ac2-300 Protein, GIG8 Protein, ID2A Protein, ID2H Protein, XId2 Protein, id2-A Protein, inhibitor of DNA binding 2 Protein, inhibitor of DNA binding 2, HLH protein Protein, inhibitor of DNA binding 2 L homeolog Protein, Id2 Protein, ID2 Protein, id2.L Protein
- Sujet
- Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Inhibits skeletal muscle and cardiac myocyte differentiation. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer. Restricts the CLOCK and ARNTL/BMAL1 localization to the cytoplasm. Plays a role in both the input and output pathways of the circadian clock: in the input component, is involved in modulating the magnitude of photic entrainment and in the output component, contributes to the regulation of a variety of liver clock-controlled genes involved in lipid metabolism.
- Poids moléculaire
- 30.9 kDa
- UniProt
- Q02363
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