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ORC4 Protein (AA 1-436, full length) (His-SUMO Tag)
ORC4
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 90 %
SDS
N° du produit ABIN5710049
Détail du produit
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Antigène
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ORC4
(Origin Recognition Complex, Subunit 4 (ORC4))
Type de proteíne
Recombinant
Attributs du protein
full length, AA 1-436
Origine
Toutes les origines à travers ORC4 Protéines
Humain
Source
Toutes les sources à travers ORC4 Protéines
Escherichia coli (E. coli)
Purification/Conjugué
Cette ORC4 protéine est marqué à la His-SUMO Tag.
Application
SDS-PAGE (SDS)
Séquence
MSSRKSKSNS LIHTECLSQV QRILRERFCR QSPHSNLFGV QVQYKHLSEL LKRTALHGES NSVLIIGPRG SGKTMLINHA LKELMEIEEV SENVLQVHLN GLLQINDKIA LKEITRQLNL ENVVGDKVFG SFAENLSFLL EALKKGDRTS SCPVIFILDE FDLFAHHKNQ TLLYNLFDIS QSAQTPIAVI GLTCRLDILE LLEKRVKSRF SHRQIHLMNS FGFPQYVKIF KEQLSLPAEF PDKVFAEKWN ENVQYLSEDR SVQEVLQKHF NISKNLRSLH MLLMLALNRV TASHPFMTAV DLMEASQLCS MDSKANIVHG LSVLEICLII AMKHLNDIYE EEPFNFQMVY NEFQKFVQRK AHSVYNFEKP VVMKAFEHLQ QLELIKPMER TSGNSQREYQ LMKLLLDNTQ IMNALQKYPN CPTDVRQWAT SSLSWL
Purification
SDS-PAGE
Pureté
> 90 %
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
0.1-2 mg/mL
Buffer
20 mM Tris-HCl based buffer, pH 8.0
Stock
-80 °C,4 °C,-20 °C
Stockage commentaire
Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Détail du antigène
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Antigène
ORC4
(Origin Recognition Complex, Subunit 4 (ORC4))
Autre désignation
ORC4 (ORC4 Produits )
Synonymes
ORC4L Protein, ORC4P Protein, Orc4P Protein, Orc4l Protein, mMmORC4 Protein, CG2917 Protein, DmORC4 Protein, Dmel\\CG2917 Protein, ORC Protein, ORC4 Protein, dmOrc4 Protein, orc4 Protein, rDmORC Protein, orc4l Protein, fc50c03 Protein, wu:fc50c03 Protein, zgc:85772 Protein, ATORC4 Protein, F23H14.9 Protein, F23H14_9 Protein, ORIGIN RECOGNITION COMPLEX SUBUNIT 4 Protein, origin recognition complex subunit 4 Protein, origin recognition complex subunit 4 Protein, origin recognition complex, subunit 4 Protein, Origin recognition complex subunit 4 Protein, origin recognition complex subunit 4 L homeolog Protein, origin recognition complex subunit Orc4 Protein, ORC4 Protein, Orc4 Protein, orc4.L Protein, orc4 Protein, CNM01830 Protein
Sujet
Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assble the pre-replication complex necessary to initiate DNA replication. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3.
Poids moléculaire
66.3 kDa
UniProt
O43929
Pathways
Mitotic G1-G1/S Phases , DNA Replication , Synthesis of DNA
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