Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Format
Liquid
Concentration
0.1-2 mg/mL
Buffer
20 mM Tris-HCl based buffer, pH 8.0
Stock
-80 °C,4 °C,-20 °C
Stockage commentaire
Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
PP2C-beta-X Protein, PP2CB Protein, PP2CBETA Protein, PPC2BETAX Protein, Pp2c2 Protein, fc18g04 Protein, ppm1a Protein, wu:fc18g04 Protein, zgc:92329 Protein, pp2c-beta-x Protein, pp2cb Protein, pp2cbeta Protein, ppc2betax Protein, zgc:92031 Protein, protein phosphatase, Mg2+/Mn2+ dependent 1B Protein, protein phosphatase 1B, magnesium dependent, beta isoform Protein, protein phosphatase, Mg2+/Mn2+ dependent, 1B Protein, protein phosphatase, Mg2+/Mn2+ dependent, 1Bb Protein, protein phosphatase, Mg2+/Mn2+ dependent 1B L homeolog Protein, protein phosphatase, Mg2+/Mn2+ dependent, 1Ba Protein, PPM1B Protein, Ppm1b Protein, ppm1bb Protein, ppm1b.L Protein, ppm1ba Protein
Sujet
Enzyme with a broad specificity. Dephosphorylates CDK2 and CDK6 in vitro. Dephosphorylates PRKAA1 and PRKAA2. Inhibits TBK1-mediated antiviral signaling by dephosphorylating it at 'Ser-172'. Plays an important role in the termination of TNF-alpha-mediated NF-kappa-B activation through dephosphorylating and inactivating IKBKB/IKKB.