PRNP Protein (AA 29-231) (His tag)
-
- Antigène Voir toutes PRNP Protéines
- PRNP (Prion Protein (PRNP))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 29-231
-
Origine
- Rat
-
Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette PRNP protéine est marqué à la His tag.
- Application
- SDS-PAGE (SDS)
- Séquence
- GGWNTGGSRY PGQGSPGGNR YPPQSGGTWG QPHGGGWGQP HGGGWGQPHG GGWGQPHGGG WSQGGGTHNQ WNKPSKPKTN LKHVAGAAAA GAVVGGLGGY MLGSAMSRPM LHFGNDWEDR YYRENMYRYP NQVYYRPVDQ YSNQNNFVHD CVNITIKQHT VTTTTKGENF TETDVKMMER VVEQMCVTQY QKESQAYYDG RRS
- Purification
- SDS-PAGE
- Pureté
- > 90 %
- Top Product
- Discover our top product PRNP Protéine
-
-
- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Stock
- -80 °C,4 °C,-20 °C
- Stockage commentaire
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
-
- Antigène
- PRNP (Prion Protein (PRNP))
- Autre désignation
- PRIO (PRNP Produits)
- Synonymes
-
ASCR Protein, AltPrP Protein, CD230 Protein, CJD Protein, GSS Protein, KURU Protein, PRIP Protein, PrP Protein, PrP27-30 Protein, PrP33-35C Protein, PrPc Protein, p27-30 Protein, Prn Protein, Prn-p Protein, prp Protein, cjd Protein, prion Protein, prp(c) Protein, MGC84114 Protein, PRP Protein, PRPC Protein, Prp Protein, SIP Protein, PRNP Protein, AA960666 Protein, AI325101 Protein, PrP
Protein, PrPC Protein, PrPSc Protein, Prn-i Protein, Sinc Protein, prP27-30 Protein, prP33-35C Protein, PrP-1 Protein, PrP1 Protein, prnprs1 Protein, stPrP-1 Protein, zgc:123004 Protein, prion protein Protein, prion protein S homeolog Protein, prion protein b Protein, PRNP Protein, Prnp Protein, prnp.S Protein, prnpb Protein - Sujet
- May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu2+ or ZN2+ for the ascorbate-mediated GPC1 deaminase degradation of its heparan sulfate side chains .
- Poids moléculaire
- 26.34 kDa
- UniProt
- P13852
- Pathways
- Transition Metal Ion Homeostasis, Activated T Cell Proliferation
-