RAD23A Protein (AA 1-363, full length) (GST tag)
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- Antigène Voir toutes RAD23A Protéines
- RAD23A (RAD23 Homolog A (RAD23A))
- Type de proteíne
- Recombinant
- Attributs du protein
- full length, AA 1-363
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette RAD23A protéine est marqué à la GST tag.
- Application
- SDS-PAGE (SDS)
- Séquence
- MAVTITLKTL QQQTFKIRME PDETVKVLKE KIEAEKGRDA FPVAGQKLIY AGKILSDDVP IRDYRIDEKN FVVVMVTKTK AGQGTSAPPE ASPTAAPESS TSFPPAPTSG MSHPPPAARE DKSPSEESAP TTSPESVSGS VPSSGSSGRE EDAASTLVTG SEYETMLTEI MSMGYERERV VAALRASYNN PHRAVEYLLT GIPGSPEPEH GSVQESQVSE QPATEAAGEN PLEFLRDQPQ FQNMRQVIQQ NPALLPALLQ QLGQENPQLL QQISRHQEQF IQMLNEPPGE LADISDVEGE VGAIGEEAPQ MNYIQVTPQE KEAIERLKAL GFPESLVIQA YFACEKNENL AANFLLSQNF DDE
- Purification
- SDS-PAGE
- Pureté
- > 90 %
- Top Product
- Discover our top product RAD23A Protéine
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Stock
- -80 °C,4 °C,-20 °C
- Stockage commentaire
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Antigène
- RAD23A (RAD23 Homolog A (RAD23A))
- Autre désignation
- RD23A (RAD23A Produits)
- Synonymes
- rad23a Protein, wu:fe11h06 Protein, zgc:92001 Protein, RAD23A Protein, HHR23A Protein, HR23A Protein, 2310040P19Rik Protein, AL024030 Protein, mHR23A Protein, RAD23 homolog A, nucleotide excision repair protein a Protein, RAD23 homolog A, nucleotide excision repair protein Protein, rad23aa Protein, RAD23A Protein, Rad23a Protein
- Sujet
- Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to 'Lys-48'-linked polyubiquitin chains in a length-dependent manner and with a lower affinity to 'Lys-63'-linked polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome.Involved in nucleotide excision repair and is thought to be functional equivalent for RAD23B in global genome nucleotide excision repair (GG-NER) by association with XPC. In vitro, the XPC:RAD23A dimer has NER activity. Can stabilize XPC.Involved in vpr-dependent replication of HIV-1 in non-proliferating cells and primary macrophages. Required for the association of HIV-1 vpr with the host proteasome.
- Poids moléculaire
- 67 kDa
- UniProt
- P54725
- Pathways
- Réparation de l'ADN
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