14-3-3 sigma/SFN Protein (AA 1-248, full length) (GST tag)
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- Antigène Voir toutes 14-3-3 sigma/SFN (SFN) Protéines
- 14-3-3 sigma/SFN (SFN) (Stratifin (SFN))
- Type de proteíne
- Recombinant
- Attributs du protein
- full length, AA 1-248
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette 14-3-3 sigma/SFN protéine est marqué à la GST tag.
- Application
- SDS-PAGE (SDS)
- Séquence
- MERASLIQKA KLAEQAERYE DMAAFMKGAV EKGEELSCEE RNLLSVAYKN VVGGQRAAWR VLSSIEQKSN EEGSEEKGPE VREYREKVET ELQGVCDTVL GLLDSHLIKE AGDAESRVFY LKMKGDYYRY LAEVATGDDK KRIIDSARSA YQEAMDISKK EMPPTNPIRL GLALNFSVFH YEIANSPEEA ISLAKTTFDE AMADLHTLSE DSYKDSTLIM QLLRDNLTLW TADNAGEEGG EAPQEPQS
- Purification
- SDS-PAGE
- Pureté
- > 90 %
- Top Product
- Discover our top product SFN Protéine
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Stock
- -80 °C,4 °C,-20 °C
- Stockage commentaire
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Antigène
- 14-3-3 sigma/SFN (SFN) (Stratifin (SFN))
- Autre désignation
- 1433S (SFN Produits)
- Synonymes
- YWHAS Protein, Er Protein, Mme1 Protein, Ywhas Protein, stratifin Protein, SFN Protein, Sfn Protein
- Sujet
- Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53.
- Poids moléculaire
- 55.2 kDa
- UniProt
- P31947
- Pathways
- Signalisation p53, Myometrial Relaxation and Contraction
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