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RRM1 Protein (AA 1-761, full length) (His-SUMO Tag)
RRM1
Origine: E. coli
Hôte: Escherichia coli (E. coli)
Recombinant
> 90 %
SDS
N° du produit ABIN5710974
Détail du produit
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Antigène
Voir toutes RRM1 Protéines
RRM1
(Ribonucleotide Reductase M1 (RRM1))
Type de proteíne
Recombinant
Attributs du protein
full length, AA 1-761
Origine
Toutes les origines à travers RRM1 Protéines
E. coli
Source
Toutes les sources à travers RRM1 Protéines
Escherichia coli (E. coli)
Purification/Conjugué
Cette RRM1 protéine est marqué à la His-SUMO Tag.
Application
SDS-PAGE (SDS)
Séquence
MNQNLLVTKR DGSTERINLD KIHRVLDWAA EGLHNVSISQ VELRSHIQFY DGIKTSDIHE TIIKAAADLI SRDAPDYQYL AARLAIFHLR KKAYGQFEPP ALYDHVVKMV EMGKYDNHLL EDYTEEEFKQ MDTFIDHDRD MTFSYAAVKQ LEGKYLVQNR VTGEIYESAQ FLYILVAACL FSNYPRETRL QYVKRFYDAV STFKISLPTP IMSGVRTPTR QFSSCVLIEC GDSLDSINAT SSAIVKYVSQ RAGIGINAGR IRALGSPIRG GEAFHTGCIP FYKHFQTAVK SCSQGGVRGG AATLFYPMWH LEVESLLVLK NNRGVEGNRV RHMDYGVQIN KLMYTRLLKG EDITLFSPSD VPGLYDAFFA DQEEFERLYT KYEKDDSIRK QRVKAVELFS LMMQERASTG RIYIQNVDHC NTHSPFDPAI APVRQSNLCL EIALPTKPLN DVNDENGEIA LCTLSAFNLG AINNLDELEE LAILAVRALD ALLDYQDYPI PAAKRGAMGR RTLGIGVINF AYYLAKHGKR YSDGSANNLT HKTFEAIQYY LLKASNELAK EQGACPWFNE TTYAKGILPI DTYKKDLDTI ANEPLHYDWE ALRESIKTHG LRNSTLSALM PSETSSQISN ATNGIEPPRG YVSIKASKDG ILRQVVPDYE HLHDAYELLW EMPGNDGYLQ LVGIMQKFID QSISANTNYD PSRFPSGKVP MQQLLKDLLT AYKFGVKTLY YQNTRDGAED AQDDLVPSIQ DDGCESGACK I
Purification
SDS-PAGE
Pureté
> 90 %
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
(cache)
Format
Liquid
Concentration
0.1-2 mg/mL
Buffer
20 mM Tris-HCl based buffer, pH 8.0
Stock
-80 °C,4 °C,-20 °C
Stockage commentaire
Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Détail du antigène
(cache)
Antigène
RRM1
(Ribonucleotide Reductase M1 (RRM1))
Autre désignation
RIR1 (RRM1 Produits )
Synonymes
CG5371 Protein, DmRNR1 Protein, Dmel\\CG5371 Protein, RNR1 Protein, RnrM1 Protein, RntL Protein, l(2)k06709 Protein, XRRM1 Protein, R1 Protein, RIR1 Protein, RR1 Protein, CHUNP6866 Protein, cb396 Protein, cb838 Protein, r1 Protein, sb:cb548 Protein, wu:fb39b07 Protein, wu:fi14b02 Protein, wu:fk95f07 Protein, ribonucleotide reductase catalytic subunit M1 Protein, Ribonucleoside diphosphate reductase large subunit Protein, ribonucleoside-diphosphate reductase large subunit Protein, ribonucleotide reductase M1 L homeolog Protein, ribonucleotide reductase M1 Protein, ribonucleotide reductase M1 polypeptide Protein, RRM1 Protein, RnrL Protein, LOC100472317 Protein, rrm1 Protein, rrm1.L Protein, Rrm1 Protein
Sujet
Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. R1 contains the binding sites for both substrates and allosteric effectors and carries out the actual reduction of the ribonucleotide. It also provides redox-active cysteines.
Poids moléculaire
101.72 kDa
UniProt
P00452
Pathways
Positive Regulation of Endopeptidase Activity
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