GCKR
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Format
Liquid
Concentration
0.1-2 mg/mL
Buffer
20 mM Tris-HCl based buffer, pH 8.0
Stock
-80 °C,4 °C,-20 °C
Stockage commentaire
Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
FGQTL5 Protein, GKRP Protein, GLRE Protein, gckr Protein, glucokinase regulator Protein, glucokinase regulatory protein Protein, glucokinase regulator L homeolog Protein, GCKR Protein, Gckr Protein, gckr.L Protein
Sujet
Inhibits glucokinase (GCK) by forming an inactive complex with this enzyme. The affinity of GCKR for GCK is modulated by fructose metabolites: GCKR with bound fructose 6-phosphate has increased affinity for GCK, while GCKR with bound fructose 1-phosphate has strongly decreased affinity for GCK and does not inhibit GCK activity.