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PSTPIP1 Protein (AA 1-416) (His tag)
PSTPIP1
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 90 % by SDS - PAGE
SDS
N° du produit ABIN5853033
Détail du produit
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Antigène
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PSTPIP1
(Proline-serine-threonine Phosphatase Interacting Protein 1 (PSTPIP1))
Type de proteíne
Recombinant
Attributs du protein
AA 1-416
Origine
Toutes les origines à travers PSTPIP1 Protéines
Humain
Source
Toutes les sources à travers PSTPIP1 Protéines
Escherichia coli (E. coli)
Purification/Conjugué
Cette PSTPIP1 protéine est marqué à la His tag.
Application
SDS-PAGE (SDS)
Séquence
MGSSHHHHHH SSGLVPRGSH MGSMMPQLQF KDAFWCRDFT AHTGYEVLLQ RLLDGRKMCK DMEELLRQRA QAEERYGKEL VQIARKAGGQ TEINSLRASF DSLKQQMENV GSSHIQLALT LREELRSLEE FRERQKEQRK KYEAVMDRVQ KSKLSLYKKA MESKKTYEQK CRDADDAEQA FERISANGHQ KQVEKSQNKA RQCKDSATEA ERVYRQSIAQ LEKVRAEWEQ EHRTTCEAFQ LQEFDRLTIL RNALWVHSNQ LSMQCVKDDE LYEEVRLTLE GCSIDADIDS FIQAKSTGTE PPAPVPYQNY YDREVTPLTS SPGIQPSCGM IKRFSGLLHG SPKTTSLAAS AASTETLTPT PERNEGVYTA IAVQEIQGNP ASPAQEYRAL YDYTAQNPDE LDLSAGDILE VILEGEDGWW TVERNGQRGF VPGSYLEKL
Pureté
> 90 % by SDS - PAGE
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
0.5 mg/mL
Buffer
Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.15M NaCl, 20 % glycerol, 1 mM DTT
Stock
4 °C,-20 °C,-80 °C
Stockage commentaire
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Détail du antigène
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Antigène
PSTPIP1
(Proline-serine-threonine Phosphatase Interacting Protein 1 (PSTPIP1))
Autre désignation
PSTPIP1 (PSTPIP1 Produits )
Synonymes
cd2bp1 Protein, cd2bp1l Protein, cd2bp1s Protein, h-pip Protein, papas Protein, pstpip Protein, PSTPIP1 Protein, CD2BP1 Protein, CD2BP1L Protein, CD2BP1S Protein, H-PIP Protein, PAPAS Protein, PSTPIP Protein, def-2 Protein, proline-serine-threonine phosphatase interacting protein 1 Protein, proline-serine-threonine phosphatase interacting protein 1 S homeolog Protein, proline-serine-threonine phosphatase-interacting protein 1 Protein, PSTPIP1 Protein, pstpip1.S Protein, pstpip1 Protein, Pstpip1 Protein
Sujet
PSTPIP1 binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, negatively affecting CD2-triggered T cell activation. The protein appears to be a scaffold protein and a regulator of the actin cytoskeleton. It has also been shown to bind ABL1, PTPN18, WAS, CD2AP, and PTPN12. Mutations in this gene are a cause of PAPA syndrome. Recombinant human PSTPIP1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Poids moléculaire
50.0kDa (439aa)
NCBI Accession
NP_003969
UniProt
O43586
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