DUSP26 Protein (AA 1-211) (His tag)

N° du produit ABIN5853235

Détail du produit

Antigène: DUSP26 (Dual Specificity Phosphatase 26 (DUSP26))

Type de proteíne: Recombinant

Attributs du protein: AA 1-211

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette DUSP26 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: MGSSHHHHHH SSGLVPRGSH MGSMCPGNWL WASMTFMARF SRSSSRSPVR TRGTLEEMPT VQHPFLNVFE LERLLYTGKT ACNHADEVWP GLYLGDQDMA NNRRELRRLG ITHVLNASHS RWRGTPEAYE GLGIRYLGVE AHDSPAFDMS IHFQTAADFI HRALSQPGGK ILVHCAVGVS RSATLVLAYL MLYHHLTLVE AIKKVKDHRG IIPNRGFLRQ LLALDRRLRQ GLEA

Pureté: > 85 % by SDS - PAGE

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Denatured

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 10 % glycerol, 0.4M urea

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: DUSP26 (Dual Specificity Phosphatase 26 (DUSP26))

Autre désignation: DuSP26 (DUSP26 Produits)

Synonymes: DUSP24 Protein, LDP-4 Protein, MKP8 Protein, NATA1 Protein, SKRP3 Protein, 2310043K02Rik Protein, Skrp3 Protein, RGD1310090 Protein, dual specificity phosphatase 26 Protein, dual specificity phosphatase 26 (putative) Protein, DUSP26 Protein, Dusp26 Protein

Sujet: DuSP26 inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity. This protein inhibits MAP kinase p38 by dephosphorylating it and inhibits p38-mediated apoptosis in anaplastic thyroid cancer cells. DuSP26 can also induce activation of MAP kinase p38 and c-Jun N-terminal kinase (JNK). Recombinant human DuSP26 protein, fused to His-tag at N-terminus, was expressed in E.coli .

Poids moléculaire: 26.3 kDa (234aa)

NCBI Accession: NP_076930

UniProt: Q9BV47