1110005A05Rik Protein, 1110018P21Rik Protein, RGD1564084 Protein, MGC82649 Protein, zgc:91928 Protein, tipin Protein, TIMELESS interacting protein Protein, timeless interacting protein Protein, timeless interacting protein S homeolog Protein, timeless interacting protein L homeolog Protein, TIPIN Protein, Tipin Protein, tipin.S Protein, tipin Protein, tipin.L Protein
Sujet
TIPIN belongs to the CSM3 family. This protein is required for normal progression of S-phase and important for cell survival after DNA damage or replication stress. TIPIN may be specifically required for the ATR-CHEK1 pathway in the replication checkpoint induced by hydroxyurea or ultraviolet light. Recombinant human TIPIN, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Poids moléculaire
36.9kDa (324 aa) confirmed by MALDI-TOF (Molecular size on SDS-PAGE will appear higher)