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TIMM8A/DDP Protein (AA 1-97) (His tag)
TIMM8A
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 90 % by SDS - PAGE
SDS
N° du produit ABIN5853449
Détail du produit
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Antigène
Voir toutes TIMM8A/DDP (TIMM8A) Protéines
TIMM8A/DDP (TIMM8A)
(Translocase of Inner Mitochondrial Membrane 8A (TIMM8A))
Type de proteíne
Recombinant
Attributs du protein
AA 1-97
Origine
Toutes les origines à travers TIMM8A/DDP Protéines
Humain
Source
Toutes les sources à travers TIMM8A/DDP Protéines
Escherichia coli (E. coli)
Purification/Conjugué
Cette TIMM8A/DDP protéine est marqué à la His tag.
Application
SDS-PAGE (SDS)
Séquence
MGSSHHHHHH SSGLVPRGSH MGSMDSSSSS SAAGLGAVDP QLQHFIEVET QKQRFQQLVH QMTELCWEKC MDKPGPKLDS RAEACFVNCV ERFIDTSQFI LNRLEQTQKS KPVFSESLSD
Pureté
> 90 % by SDS - PAGE
Top Product
Discover our top product TIMM8A Protéine
Alternatives
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.15M NaCl, 30 % glycerol, 1 mM DTT
Stock
4 °C,-20 °C,-80 °C
Stockage commentaire
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Détail du antigène
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Antigène
TIMM8A/DDP (TIMM8A)
(Translocase of Inner Mitochondrial Membrane 8A (TIMM8A))
Autre désignation
TIMM8A (TIMM8A Produits )
Synonymes
TIMM8A Protein, ddp Protein, tim8a Protein, timm8a Protein, DDP Protein, DDP1 Protein, DFN1 Protein, MTS Protein, TIM8 Protein, im:6896085 Protein, zgc:100916 Protein, Ddp1 Protein, Timm8a Protein, DXHXS1274E Protein, Fci-12 Protein, Tim8a Protein, translocase of inner mitochondrial membrane 8 homolog A (yeast) Protein, translocase of inner mitochondrial membrane 8A Protein, translocase of inner mitochondrial membrane 8 homolog A1 (yeast) Protein, translocase of inner mitochondrial membrane 8A1 Protein, TIMM8A Protein, timm8a Protein, Timm8a1 Protein
Sujet
TIMM8A is involved in the import and insertion of hydrophobic membrane proteins from the cytoplasm into the mitochondrial inner membrane. The gene is mutated in Mohr-Tranebjaerg syndrome/Deafness Dystonia Syndrome (MTS/DDS) and it is postulated that MTS/DDS is a mitochondrial disease caused by a defective mitochondrial protein import system. Defects in this gene also cause Jensen syndrome, an X-linked disease with opticoacoustic nerve atrophy and muscle weakness. This protein, along with TIMM13, forms a 70 kDa heterohexamer. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Recombinant human TIMM8A proten, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Poids moléculaire
13.4kDa (120aa) confirmed by MALDI-TOF
NCBI Accession
NP_004076
UniProt
O60220
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