Calpain S1 Protein (AA 84-268) (His tag)

N° du produit ABIN5853704

Détail du produit

Antigène: Calpain S1 (CAPNS1) (Calpain, Small Subunit 1 (CAPNS1))

Type de proteíne: Recombinant

Attributs du protein: AA 84-268

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette Calpain S1 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: MGSSHHHHHH SSGLVPRGSH MGSRTHYSNI EANESEEVRQ FRRLFAQLAG DDMEVSATEL MNILNKVVTR HPDLKTDGFG IDTCRSMVAV MDSDTTGKLG FEEFKYLWNN IKRWQAIYKQ FDTDRSGTIC SSELPGAFEA AGFHLNEHLY NMIIRRYSDE SGNMDFDNFI SCLVRLDAMF RAFKSLDKDG TGQIQVNIQE WLQLTMYS

Pureté: > 95 % by SDS - PAGE

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.15M NaCl, 20 % glycerol, 1  mM DTT

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: Calpain S1 (CAPNS1) (Calpain, Small Subunit 1 (CAPNS1))

Autre désignation: CAPNS1 (CAPNS1 Produits)

Synonymes: 30K Protein, CALPAIN4 Protein, CANP Protein, CANPS Protein, CAPN4 Protein, CDPS Protein, CSS1 Protein, Capn4 Protein, CAPNS1 Protein, Capa-4 Protein, Capa4 Protein, D7Ertd146e Protein, MGC84330 Protein, capns1 Protein, cb616 Protein, wu:fb81g08 Protein, wu:fl09e04 Protein, zgc:110603 Protein, calpain small subunit 1 Protein, calpain, small subunit 1 Protein, calpain, small subunit 1 L homeolog Protein, calpain, small subunit 1 a Protein, CAPNS1 Protein, Capns1 Protein, capns1.L Protein, capns1a Protein

Sujet: Calpains are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes. Recombinant human CAPNS1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Poids moléculaire: 23.8kDa (208aa) confirmed by MALDI-TOF

NCBI Accession: NP_001740

UniProt: P04632

Pathways: Apoptose