Caspase 2 Protein (AA 348-452) (His tag)
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- Antigène Voir toutes Caspase 2 (CASP2) Protéines
- Caspase 2 (CASP2) (Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 348-452
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette Caspase 2 protéine est marqué à la His tag.
- Application
- SDS-PAGE (SDS)
- Séquence
- MGSSHHHHHH SSGLVPRGSH MAGKEKLPKM RLPTRSDMIC GYACLKGTAA MRNTKRGSWY IEALAQVFSE RACDMHVADM LVKVNALIKD REGYAPGTEF HRCKEMSEYC STLCRHLYLF PGHPPT
- Pureté
- > 80 % by SDS - PAGE
- Top Product
- Discover our top product CASP2 Protéine
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Commentaires
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Denatured
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.0 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.4M urea, 10 % glycerol
- Stock
- 4 °C,-20 °C,-80 °C
- Stockage commentaire
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Antigène
- Caspase 2 (CASP2) (Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))
- Autre désignation
- CASP2 (CASP2 Produits)
- Synonymes
- xCaspase-2 Protein, Caspase-2 Protein, ICH-1 Protein, Nedd2 Protein, CASP-2 Protein, ICH1 Protein, NEDD-2 Protein, NEDD2 Protein, PPP1R57 Protein, ICH-1L/1S Protein, ICH1L1S Protein, caspase 2 Protein, caspase 2 L homeolog Protein, caspase-2 Protein, CASP2 Protein, casp2.L Protein, CpipJ_CPIJ008254 Protein, Casp2 Protein
- Sujet
- CASP2 is a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The proteolytic cleavage of this protein is induced by a variety of apoptotic stimuli. Alternative splicing of this gene results in multiple transcript variants that encode different isoforms. Recombinant human CASP2 protein, fused to His-tag at N-terminus, was expressed in E.coli .
- Poids moléculaire
- 14.1kDa (126aa)
- NCBI Accession
- NP_116764
- UniProt
- P42575
- Pathways
- Apoptose, Caspase Cascade in Apoptosis, Neurotrophin Signaling Pathway
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