BP-8 Protein, CSDA2 Protein, CSDB Protein, DBPB Protein, MDR-NF1 Protein, NSEP-1 Protein, NSEP1 Protein, YB-1 Protein, YB1 Protein, Byb1 Protein, Cbfa Protein, Dbpb Protein, Ef1a Protein, Msy1 Protein, Nsep1 Protein, Yb1 Protein, bp-8 Protein, csda2 Protein, csdb Protein, dbpb Protein, frgy1 Protein, mdr-nf1 Protein, nsep-1 Protein, nsep1 Protein, yb1 Protein, 1700102N10Rik Protein, C79409 Protein, EF1A Protein, MSY1 Protein, dbpB Protein, mYB-1a Protein, nuclease sensitive element binding protein 1 Protein, Y-box binding protein 1 Protein, Y box binding protein 1 Protein, Y-box binding protein 1 S homeolog Protein, nuclease-sensitive element-binding protein 1 Protein, Y box protein 1 Protein, nsep1 Protein, YBX1 Protein, Ybx1 Protein, ybx1.S Protein, LOC479011 Protein
Sujet
YBX1, also known as Y box binding protein 1, associates with the selenocysteine insertion sequence and functions in mammalian selenoprotein translation. This protein is a potential drug target in cancer therapy. It helps the replication of adenovirus type 5, a commonly used vector in gene therapy. Thus, YBX1 can cause an oncolytic effect in YBX1 positive cancer cells treated with adenoviruses. Recombinant human YBX1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
Poids moléculaire
38.3 kDa (347aa) confirmed by MALDI-TOF (Molecular size on SDS-PAGE will appear higher)