UGT1A1 Protein (AA 26-490) (His tag)

N° du produit ABIN5854140

Détail du produit

Antigène: UGT1A1 (UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1))

Type de proteíne: Recombinant

Attributs du protein: AA 26-490

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette UGT1A1 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: MGSSHHHHHH SSGLVPRGSH MGSHAGKILL IPVDGSHWLS MLGAIQQLQQ RGHEIVVLAP DASLYIRDGA FYTLKTYPVP FQREDVKESF VSLGHNVFEN DSFLQRVIKT YKKIKKDSAM LLSGCSHLLH NKELMASLAE SSFDVMLTDP FLPCSPIVAQ YLSLPTVFFL HALPCSLEFE ATQCPNPFSY VPRPLSSHSD HMTFLQRVKN MLIAFSQNFL CDVVYSPYAT LASEFLQREV TVQDLLSSAS VWLFRSDFVK DYPRPIMPNM VFVGGINCLH QNPLSQEFEA YINASGEHGI VVFSLGSMVS EIPEKKAMAI ADALGKIPQT VLWRYTGTRP SNLANNTILV KWLPQNDLLG HPMTRAFITH AGSHGVYESI CNGVPMVMMP LFGDQMDNAK RMETKGAGVT LNVLEMTSED LENALKAVIN DKSYKENIMR LSSLHKDRPV EPLDLAVFWV EFVMRHKGAP HLRPAAHDLT WYQYHSLD

Pureté: > 90 % by SDS - PAGE

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Denature

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid, In 20  mM Tris-HCl (  pH 8.0) containing 10 % glycerol

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: UGT1A1 (UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1))

Autre désignation: uGT1A1 (UGT1A1 Produits)

Synonymes: BILIQTL1 Protein, GNT1 Protein, HUG-BR1 Protein, UDPGT Protein, UDPGT 1-1 Protein, UGT1 Protein, UGT1A Protein, Gnt1 Protein, UGT1A01 Protein, Udpgt-1a Protein, UgtBr1 Protein, Udpgt Protein, Ugt1 Protein, zgc:123097 Protein, UDP glucuronosyltransferase family 1 member A1 Protein, UDP glucuronosyltransferase 1 family, polypeptide A1 Protein, UDP-glucuronosyltransferase 1-1 Protein, UDP-glucuronosyltransferase Protein, UDP-glucuronosyltransferase 1-6 Protein, UDP glucuronosyltransferase 1 family polypeptide a1 Protein, UGT1A1 Protein, Ugt1a1 Protein, LOC100065342 Protein, LOC100125517 Protein, LOC100229734 Protein, LOC100405984 Protein, LOC100511479 Protein, ugt1a1 Protein

Sujet: UGT1A1 also known as uDP-glucuronosyltransferase 1-1. uGT1A1 is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. It is also able to catalyze glucuronidation of 17beta-estradiol, 17alpha-ethinylestradiol, 1-hydroxypyrene, 4-methylumbelliferone, 1-naphthol, paranitrophenol, scopoletin, and umbelliferone. Recombinant human uGT1A1, fused to His-tag at N-terminus, was expressed in E.coli.

Poids moléculaire: 54.7kDa (488aa)

NCBI Accession: NP_000454

UniProt: P22309

Pathways: Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha