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PEBP1 Protein (AA 1-187) (His tag)
PEBP1
Origine: Souris
Hôte: Escherichia coli (E. coli)
Recombinant
> 95 % by SDS - PAGE
SDS
N° du produit ABIN5854348
Détail du produit
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Antigène
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PEBP1
(Phosphatidylethanolamine Binding Protein 1 (PEBP1))
Type de proteíne
Recombinant
Attributs du protein
AA 1-187
Origine
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Souris
Source
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Escherichia coli (E. coli)
Purification/Conjugué
Cette PEBP1 protéine est marqué à la His tag.
Application
SDS-PAGE (SDS)
Séquence
MGSSHHHHHH SSGLVPRGSH MGSMAADISQ WAGPLCLQEV DEPPQHALRV DYAGVTVDEL GKVLTPTQVM NRPSSISWDG LDPGKLYTLV LTDPDAPSRK DPKFREWHHF LVVNMKGNDI SSGTVLSDYV GSGPPSGTGL HRYVWLVYEQ EQPLSCDEPI LSNKSGDNRG KFKVETFRKK YNLGAPVAGT CYQAEWDDYV PKLYEQLSGK
Pureté
> 95 % by SDS - PAGE
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol
Stock
4 °C,-20 °C,-80 °C
Stockage commentaire
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Détail du antigène
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Antigène
PEBP1
(Phosphatidylethanolamine Binding Protein 1 (PEBP1))
Autre désignation
Pebp1 (PEBP1 Produits )
Synonymes
HCNP Protein, HCNPpp Protein, PBP Protein, PEBP Protein, PEBP-1 Protein, RKIP Protein, pbp Protein, hcnp Protein, pebp Protein, rkip Protein, Pbp Protein, Pbp1 Protein, Pbpr Protein, Rkip Protein, PEBP1 Protein, BcDNA:LP12095 Protein, CG18594 Protein, Dmel\\CG18594 Protein, T2 Protein, zgc:56033 Protein, zgc:76942 Protein, phosphatidylethanolamine binding protein 1 Protein, phosphatidylethanolamine binding protein 1 L homeolog Protein, phosphatidylethanolamine-binding protein Protein, phosphatidylethanolamine-binding protein,putative Protein, Phosphatidylethanolamine-binding protein 1 Protein, PEBP1 Protein, pebp1 Protein, Pebp1 Protein, pebp1.L Protein, RR_RS07785 Protein, PVX_235290 Protein, PVX_123630 Protein, PKH_143640 Protein, EAM_1207 Protein
Sujet
Pebp1 also known as Phosphatidylethanolamine-binding protein 1. The protein Binds with ATP, opioids and phosphatidylethanolamine. Pebp1 exerts inhibitory activity against several serine proteases including thrombin, neuropsin, and chymotrypsin, it also inhibits the kinase activity of RAF1 by inhibiting its activation and by dissociating the RAF1/MEK complex and acting as a competitive inhibitor of MEK phosphorylation. Also, targeting Pebp1 levels can delay photoreceptor degeneration, assisting in extending the time-window for treating such rapidly progressing blindness disorder. Recombinant mouse Pebp1, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Poids moléculaire
23.2kDa (210aa) confirmed by MALDI-TOF
NCBI Accession
NP_061346
UniProt
P70296
Pathways
Feeding Behaviour
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