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EPOR Protein (AA 25-250) (His tag)
EPOR
Origine: Humain
Hôte: Baculovirus infected Insect Cells
Recombinant
> 95 % by SDS - PAGE
SDS
N° du produit ABIN5854452
Détail du produit
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Antigène
Voir toutes EPOR Protéines
EPOR
(Erythropoietin Receptor (EPOR))
Type de proteíne
Recombinant
Attributs du protein
AA 25-250
Origine
Toutes les origines à travers EPOR Protéines
Humain
Source
Toutes les sources à travers EPOR Protéines
Baculovirus infected Insect Cells
Purification/Conjugué
Cette EPOR protéine est marqué à la His tag.
Application
SDS-PAGE (SDS)
Séquence
APPPNLPDPK FESKAALLAA RGPEELLCFT ERLEDLVCFW EEAASAGVGP GNYSFSYQLE DEPWKLCRLH QAPTARGAVR FWCSLPTADT SSFVPLELRV TAASGAPRYH RVIHINEVVL LDAPVGLVAR LADESGHVVL RWLPPPETPM TSHIRYEVDV SAGNGAGSVQ RVEILEGRTE CVLSNLRGRT RYTFAVRARM AEPSFGGFWS AWSEPVSLLT PSDLDPHHHH HH
Pureté
> 95 % by SDS - PAGE
niveau d'endotoxine
< 1.0 EU per 1 microgram of protein (determined by LAL method)
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
0.5 mg/mL
Buffer
Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
Stock
4 °C,-20 °C,-80 °C
Stockage commentaire
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Détail du antigène
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Antigène
EPOR
(Erythropoietin Receptor (EPOR))
Autre désignation
Erythropoietin receptor (EPOR Produits )
Synonymes
EPOR Protein, epor Protein, EPO-R Protein, erythropoietin receptor Protein, erythropoietin receptor L homeolog Protein, EPOR Protein, epor Protein, Epor Protein, epor.L Protein
Sujet
EPOR, also known as Erythropoietin receptor, mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, it dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. So it may also activate the LYN tyrosine kinase. Recombinant human EPOR, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Poids moléculaire
25.6kDa (232aa) 28-40kDa (SDS-PAGE under reducing conditions)
NCBI Accession
NP_000112
UniProt
P19235
Pathways
Signalistation JAK/STAT
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